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Edoxaban prevents blood coagulation by blocking the factor Xa Enzyme. The factor Xa enzyme is responsible for the formation of the blood clots. However, when an anticoagulant such as edoxaban is used, it will block the factor Xa Enzyme from forming the thrombin. Thrombin is a substance that is responsible for clotting the blood by sticking the blood platelets to one another. Edoxaban breaks this chain by blocking the Factor Xa Enzyme, resulting in the decreased formation of thrombin, thereby reducing blood coagulation.

CVR Life Sciences

Mechanism of action:

It is used to treat the condition called non-valvular atrial fibrillation which is caused due to irregular heartbeats. As a result, there is a chance of the formation of blood clots in the heart which can further lead to stroke. Edoxaban which is an active oral anticoagulant when used in such conditions will reduce blood coagulation and can prevent stroke and systemic embolism.

It is also used to treat patients who suffer from the condition called deep vein thrombosis and pulmonary embolism after they have been treated with the injectable blood thinner drug for around 5-10 days. Deep Vein Thrombosis is a condition that happens due to the formation of blood clots in the veins located deep inside the body. Pulmonary Embolism is a condition that occurs due to the formation of blood clots in the lungs. But when edoxaban is used it can reduce blood coagulation and prevent further severe health complications.


Edoxaban may interact with other medications which results in the change of the functionality of the drug and can have certain severe effects. A few of the side effects that occur due to the usage of edoxaban are bleeding, bruising, skin rashes, tiredness, and headache. However, it is very important to use the edoxaban under the proper guidance and instruction of health practitioners or doctors. This is because as the symptoms of each person would differ from one to another, there might be variations in the health conditions. Therefore it is very important to use the medication after doing the proper diagnosis and seeking the guidance of the doctor.

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